Question & Answers For:

Tangential Flow Filtration System

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q.

What is Tangential Flow Filtration (TFF) and how does it work?

a.

Tangential Flow Filtration (TFF) is a filtration process where the liquid flows tangentially across the surface of the filter membrane, rather than directly through it. This method helps to separate particles or molecules based on size, allowing for high-efficiency filtration, concentration, and purification. It minimizes membrane fouling by keeping particles in motion during the process.

 

q.

What are the benefits of using the ÄKTA Crossflow system for filtration?

a.

The ÄKTA Crossflow system provides automated control, making it easier to scale up processes, optimize filtration parameters, and improve productivity. It offers efficient filtration, reduces membrane fouling, and enhances throughput, making it ideal for both small-scale research and large-scale processing applications.

 

q.

Can the Tangential Flow Filtration System handle different types of samples or fluids?

a.

Yes, the Tangential Flow Filtration System is versatile and can handle a wide range of sample types and fluids, including biological solutions, pharmaceuticals, and industrial applications. It is designed to filter different sizes of particles or molecules with high efficiency.

 

q.

How does the system ensure optimal performance during process development?

a.

The ÄKTA Crossflow system is automated, offering precise control over the filtration parameters, such as pressure, flow rate, and temperature. This allows for consistent, reproducible results, and the ability to fine-tune processes to achieve the best filtration performance and optimize your process development.

 

q.

Is the system suitable for both research and commercial-scale applications?

a.

Yes, the Tangential Flow Filtration System is ideal for both small-scale research and large-scale processing. It is designed to be scalable, offering flexibility for various stages of development and production, making it suitable for a wide range of industries, from lab-scale research to commercial applications.

 

q.

How does the system help in filter screening and optimization?

a.

The ÄKTA Crossflow system streamlines the filter screening and optimization process by automating key steps, reducing the need for manual intervention. It allows users to quickly test different filters and optimize conditions to ensure the best filtration results for their specific applications.

 

q.

What makes this system a good choice for process development?

a.

The Tangential Flow Filtration System is ideal for process development because it combines automation with advanced filtration capabilities. It accelerates testing, improves reproducibility, and enables efficient scale-up of filtration processes, making it an excellent choice for developing and optimizing filtration processes.

 

q.

Can the system be used for continuous processing?

a.

Yes, the ÄKTA Crossflow system is designed for continuous processing, allowing for uninterrupted filtration. This capability is ideal for applications where high throughput and consistent processing are required, such as in biopharmaceutical production or other industrial applications.

 

q.

Is the system easy to operate for someone without a technical background?

a.

The ÄKTA Crossflow system is designed with user-friendly interfaces and automation features, making it relatively easy to operate even for individuals without a technical background. The system provides guided workflows and clear instructions, which simplify operation and reduce the need for in-depth technical knowledge.

 

q.

What types of filters are compatible with the system?

a.

The Tangential Flow Filtration System is compatible with a wide range of filter types, including membrane filters for ultrafiltration, microfiltration, and nanofiltration. Users can select filters that best suit their specific application, depending on the size and type of particles or molecules being processed.